منابع مشابه
Severe Cutaneous Adverse Reactions
Severe cutaneous adverse reactions (SCARs) are generally induced by drugs and encompass the conditions of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), drug induced eosinophilia and systemic syndrome (DRESS) also known as drug induced hypersensitivity syndrome (DIHS), and acute generalized exanthematous pustulosis (AGEP). These conditions, although rare, cause significant...
متن کاملTreatments for Severe Cutaneous Adverse Reactions
Severe cutaneous adverse reaction (SCAR) is life-threatening. It consists of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (GBFDE). In the past years, emerging studies have provided better understandings regarding the pat...
متن کاملSevere cutaneous adverse reactions to drugs.
PURPOSE OF REVIEW This paper updates the treatment of Stevens-Johnson syndrome and toxic epidermal necrolysis supported by relevant views about the pathogenesis. RECENT FINDINGS Building on the thesis that Stevens-Johnson syndrome and toxic epidermal necrolysis are due to dermal cell apoptosis, molecular pathways that may lead to this have been proposed. Intravenous immunoglobulin is postulat...
متن کاملAllopurinol-induced severe cutaneous adverse reactions.
In their article entitled ‘Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin’, Chung and colleagues elegantly investigated the factors associated with severe cutaneous adverse reactions (SCAR) in patients taking allopurinol as antihyperuricaemic agent and found that impai...
متن کاملAnticonvulsant Drugs and Severe Adverse Cutaneous Drug Reactions: A Longitudinal Observational Study
Background: Severe Adverse Cutaneous Reactions to Drugs (SACRDs) are skin eruptions due to drugs, which can cause morbidity and morbidity in patients. Objectives: The aim of this study was to determine the offending drug/agents and clinical phenotypes of SACRDs leading to admissions to the hospital. Materials & Methods: We conducted a retrospective cross-sectional study during one year (March...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology
سال: 2011
ISSN: 0378-6323
DOI: 10.4103/0378-6323.74963